More Clinical Mimics of Infant Botulism
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چکیده
منابع مشابه
Clinical Mimics of Infant Botulism
Since 1992, Human Botulism Immune Globulin has been provided by the California Department of Health Services to infants with probable infant botulism, the intestinal toxemia form of human botulism. Human Botulism Immune Globulin became available in California in 1992–1997 within a randomized, controlled, double-blinded, pivotal clinical trial and subsequently became available nationwide in 1998...
متن کاملClinical mimics of infant botulism.
Since 1992, Human Botulism Immune Globulin has been provided by the California Department of Health Services to infants with probable infant botulism, the intestinal toxemia form of human botulism. Human Botulism Immune Globulin became available in California in 1992-1997 within a randomized, controlled, double-blinded, pivotal clinical trial and subsequently became available nationwide in 1998...
متن کاملInfant botulism.
Infant botulism is a rare disease that affects infant less than 12 months of age. The illness results from absorption of botulinum toxin produced in situ by neurotoxigenic clostridia that can temporarily colonize the intestinal tract of infants. To date, all inhabited continents except Africa have reported cases of infant botulism. Recognition of cases seem directly related to physician awarene...
متن کاملInfant Botulism: a Summary
Infant botulism is a rare paralytic disease caused by the microorganism Clostridium botulinum. If an infant swallows enough spores, the spores can colonize the large intestine, multiply and produce toxin. The toxin is absorbed into the body and carried to the nerve endings, which results in muscular impairment. Infant botulism differs from foodborne botulism in where and when the toxin is produ...
متن کامل[Human botulism immuneglobulin for the treatment of infant botulism].
BACKGROUND We created the orphan drug Human Botulism Immune Globulin Intravenous (Human) (BIG-IV), which neutralizes botulinum toxin, and evaluated its safety and efficacy in treating infant botulism, the intestinal-toxemia form of human botulism. METHODS We performed a five-year, randomized, double-blind, placebo-controlled trial statewide, in California, of BIG-IV in 122 infants with suspec...
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ژورنال
عنوان ژورنال: The Journal of Pediatrics
سال: 2018
ISSN: 0022-3476
DOI: 10.1016/j.jpeds.2017.09.044